![]() Hence, all the reported cases of tumour-related TGA might in fact be instances of TEA. The execution of 24-h EEG is valuable in the diagnostic work up of patients with sudden-onset amnesic episodes. The recurrence and the presence of symptoms other than amnesia are key features able to discriminate between TEA and transient global amnesia (TGA). These features - short duration of symptoms (<2 h), stereotyped semiology, and high recurrence rate - are all typical of TEA as opposed to TGA. Transient epileptic amnesia (TEA) is a focal epilepsy of temporal origin. We designed this study to evaluate the actual frequency of TEA in a real-life scenario and to highlight the features that can help clinicians. Alternatively, it is recognised that a subset of ‘pure TGA' patients, largely identifiable because of atypically brief or recurrent attacks, develop epilepsy and/or respond to antiepileptic medication. Transient epileptic amnesia (TEA) is an underestimated condition in emergency clinical setting, where most of transient amnesic episodes tend to be classified as transient global amnesia (TGA). In other words, the tumour might lower the threshold for the clinical manifestation of vascular and/or epileptiform events. ![]() Such localised neoplastic lesions might result in abnormal electrical activity within medial temporal lobe networks, hence producing TEA-like events, and also compromise medial temporal lobe blood supply, for example in association with exercise, and hence predispose to typical TGA-like events. It is characterized by an episode of anterograde and retrograde amnesia lasting. ![]() In some cases, the finding of a tumour is unlikely to be any more than chance concurrence, based on tumour location distant from memory-eloquent structures, whereas other tumour locations are more obviously of possible pathophysiological relevance. Transient global amnesia (TGA) has been described since the 19th century. What is the clinical significance of these reports of TGA and brain tumour? Some reports fail to meet the clinical criteria for TGA whereas others have features which might be more in keeping with TEA. Transient global amnesia (TGA) is a temporary memory loss characterized by an abrupt onset of antero-grade and retrograde amnesia, totally reversible.
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